Sialic Acid Products

Neuraminidases(Sialidases)


N-acetylneuraminic Acid Quantitation Kit

Contains all the reagents needed to quickly and accurately quantitate sialic acids, including N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA). This kit includes reagent for 25 assays, each assay measuring from 1-200 nmoles of sialic acid.

GE57 N-acetylneuraminic Acid Quantitation Kit datasheet pdf




N-Acetylneuraminic Acid Aldolase

N-Acetylneuraminic Acid Aldolase (N-Acetylneuraminate pyruvate lyase, EC 4.1.3.3) is found in several bacterial strains which use the reverse reaction to degrade N-acetylneuraminic acid (sialic acid). N-acetylneuraminic Acid Aldolase catalyzes the reversible reaction:

N-acetylneuraminic acid ↔ N-acetylmannosamine + Pyruvic acid

The forward reaction is particularly useful for the determination of N-acetylneuraminic acid concentrations by quantitatively converting it to N-acetylmannosamine and pyruvate. Since N-acetylneuraminic acid is both negatively charged and not a reducing sugar, its direct analysis is more difficult than conventional sugars. N-acetylmannosamine, however, can be assayed as a conventional reducing sugar by various techniques such as flourescent dye or
radioactive labeling.

100 U/ml - 6 U for 60 μL

GE10 datasheet pdf




CMP-N-Acetylneuraminic Acid
Synthetase


CMP-N-acetylneuraminic acid synthetase (EC 2.7.7.43) catalyzes the formation of CMP-N-acetylneuraminic acid (CMP-NANA) and inorganic pyrophosphate from CTP and N-acetylneuraminic acid. It is useful for production of CMP-NANA for use as a donor molecule in sialic acid transferase reactions and in coupled transferase reactions.

9 U/ml - 540 mU for 60 μL

GE11 datasheet pdf