Sialidases



α(2-3) Neuraminidase

α(2-3) Neuraminidase (N-acetylneuraminate glycohydrolase EC 3.2.1.18) cleaves exclusively the non-reducing terminal α(2-3) unbranched sialic acid residues from complex carbohydrates and glycoproteins. There is no detectable activity on α(2-6) or α(2-8) linkages or on branched α(2-3) linkages (see Figure 1). To cleave all non-reducing terminal sialic acid residues including branched sialic acids (linked to an internal residue) from complex carbohydrates and glycoproteins, use α(2-3,6,8,9) Neuraminidase

5 U/ml - 300 mU for 60 μL

GE20 datasheet in pdf



α(2-3, 6) Neuraminidase

α2-3, 6) Neuraminidase (N-acetylneuraminate glycohydrolase, EC 3.2.1.18) cleaves all non-reducing terminal non-branched α(2-3)- and α(2-6) sialic acid residues from complex carbohydrates and glycoproteins. There is no detectable activity on α (2-8) or α(2-9) linkages or on branched α(2-3) or α(2-6) linkages. The relative cleavage rates for different linkages are: α(2-3) > α(2-6).

15 U/ml - 900 mU for 60 μL

GE24 datasheet in pdf



α(2-3, 6, 8, 9) Neuraminidase

α (2-3, 6, 8, 9) neuraminidase (EC 3.2.1.18) cleaves all cleaves all non-reducing terminal sialic acid residues from complex carbohydrates and glycoproteins. The relative cleavage rates for different linkages are: α(2-6) > α(2-3) > α(2-8), α(2-9).

5 U/ml - 300 mU for 60 μL

GE23 datasheet in pdf